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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Dendritic Cells (DCs) & SLC5A8 / Sodium-Coupled Monocarboxylate Transporter 1 (SMCT1)

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Dendritic Cells (DCs) have the SLC5A8 / Sodium-Coupled Monocarboxylate Transporter 1 (SMCT1).
Gurav et al. 2015 Biochem J. 469(2): 267-278…

Blockade of dendritic cell development by bacterial fermentation products butyrate and propionate through a transporter (Slc5a8)-dependent inhibition of histone deacetylases
Singh et al. 2010 Journal of Biological Chemistry. 285:27601-27608
Slc5a8, a Na+-coupled high-afﬁnity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and CRC under low-ﬁbre dietary conditions
Gurav et al. 2015 Biochem J. 469(2): 267-278

5/29/2026