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Autoimmune Diseases & Gut microbiota
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Microbiota can trigger autoimmunity directly by providing antigenic stimuli, resulting in cross-reactivityof autoreactive lymphocytes and autoantibodies with bacterial orthologs.
Hundreds of studies have been conducted to understand better the link between the microbiome and autoimmunity, including studies explicitly targeting inflammatory bowel disease (IBD), multiple sclerosis (MS), rheumatoid arthritis (RA), [ty…
References (Sources)
- Crohn disease–associated adherent-invasive E. coli bacteria target mouse and human Peyer’s patches via long polar fimbriae
- Distinct fecal and oral microbiota composition in human type 1 diabetes, an observational study.
- Fecal microbiota composition differs between children with beta-cell autoimmunity and those without
- Intestinal Microbiome in Hematopoietic Stem Cell Transplantation For Autoimmune Diseases: Considerations and Perspectives on Behalf of Autoimmune Diseases Working Party (ADWP) of the EBMT
- The Human Microbiome and Obesity: Moving beyond Associations
- The microbiome and autoimmunity: a paradigm from the gut-liver axis
- The Role of Gut Microbiota and Environmental Factors in Type 1 Diabetes Pathogenesis