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Cholesterol absorption is a complex physiological process influenced by various factors, including diet, genetic predisposition, and the interaction with other sterols.
Cholesterol is solubilized in bile salt micelles in the intestinal lumen. This solubilization is crucial for its absorption. The efficiency of this process can be influenced by the presence of other sterols, such as plant sterols, which compete for incorporation into micelles and can reduce cholesterol solubility
Some cholesterol is excreted back into the intestinal lumen via [ATP-binding cassette (ABC) transporters / ABC transpo…