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Tumor-Infiltrating Lymphocytes (TILs) can also be inhibited by tumor-derived metabolic waste products and low oxygen.
Preexisting lymphocytic infiltration of tumors is associated with superior prognostic outcomes in various cancers
Zamarin et al. 2014
Strong lymphocyte infiltration is associated with antitumor response and improved clinical outcome.
High density Cytotoxic T cell (CTL) intratumoral is associated with favorbable patient outcome
see also:
[Anti-tumor immune responses](brain://syICu…