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Hepatic Inflammation / Liver Inflammation & Hepatobiliary cancers

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Chronic liver inflammation can lead to the development of hepatobiliary cancers, including hepatocellular carcinoma (HCC), intrahepatic cholangiocarcinoma (iCCA), and combined HCC-CCA (cHCC-CCA).
Leone et al. 2021 Trends in Cancer 7: 606

Oxidative stress triggers hepatocyte damage, proliferation, and eventually cancer initiation and sustainment.
Leone et al. 2021 Trends in Cancer 7: 606

In the context of chronic liver inflammatory diseases, a prolo…