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All immune cells can respond to signals via pattern recognition receptors, antigen receptors, and/or cytokine/growth factor receptors. These signals can induce a switch from a resting state to an activated state.
Activation is associated with cell proliferation and/or acquisition of effector functions
The receptors are directly linked to transcription factors, which can alter gene expression.
There are several of targeted pathways involved in development, activation, differentiation & function of immune cells
Vanneman & Dranoff 2012
see also:
[Immune Cells & Pattern Recogni…