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Elastase refers to a group of proteolytic enzymes (proteases) primarily known for degrading elastin, an essential protein in connective tissue that provides elasticity and resilience. The two main human forms are neutrophil elastase and pancreatic elastase, each with distinct biological functions and clinical implications.
Pancreatic Elastase: Secreted by the pancreas, this enzyme aids in digestion by breaking down protein in food. Clinical uses include measurement in stool to assess pancreatic function
Neutrophil Elastase (NE): Produced and stored in neutrophils, NE is released during inflammation and infection to help break down bacteria and tissue d…