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In a high-fat diet, adipocytes and, hence, adipose tissue proliferate dramatically. Adipocyte hypertrophy is associated with endoplasmic reticulum stress, which leads to cell death and monocyte recruitment.
The main cause of adiposity / obesity is a high-fat diet (HFD)
Adiposity / Obesity represents a consequence of abnormal fat accumulation in the body, resulting in high [energy](brain:…