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The ligand of Programmed cell death protein 1 (PD-1) Programmed death-ligand 1 (PD-L1) is a member of the B7 gene family.
Programmed death-ligand 1 (PD-L1) is highly expressed on the surface of tumor cells, by antigen-presenting cells , including human peripheral blood monocytes stimulated with interferon gamma , and activated human and murine dendritic cells and binds to Programmed cell death protein 1 (PD-1) on the surface of activated T cells, leading to suppression of T cells.
In addition, Programmed death-ligand 1 (PD-L…