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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Peroxisome proliferator-activated receptor gamma (PPAR-gamma)

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Peroxisome proliferator-activated receptor gamma (PPAR-gamma) activates mitochondrial beta-oxidation of long-chain and short-chain fatty acids (SCFAs), resulting in oxygen consumption through oxidative phosphorylation
Roediger 1980 Gut 21: 793-798
Donohoe et al. 2011 Cell Metab 13(5): 517-526
Duszka et al. 2017 Int. J. Mol. Sci. 18: 2559

Peroxisome proliferator-activated receptor gamma (PPAR-gamma) can inhibit the transcription of proinflammatory genes, including the iNOS gene (Nos2)
Li et al. 2000 Mol. Cell. Biol. 20: 4699

Peroxisome proliferator-activated receptor gamma (PPAR-gamma) is a nuclear receptor protein that plays a vital role in cell differentiation and metabolism. Its activation has been linked to antitumor effects in several types of cancer.
Zhang et al. 2019 Cell Death Dis. 10(6): 404

References (Sources)

Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ
Zhang et al. 2019 Cell Death Dis. 10(6): 404
Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors
Francque et al. 2021 Nature Reviews GASTROENTEROLOG & HEPATOLOGY 18: 24
Review
Peroxisome proliferator-activated receptor gamma is induced during differentiation of colon epithelium cells
Lefebvre et al 1999 J. Endocrinol. 162: 331
Peroxisome Proliferator-Activated Receptor γ-Dependent Repression of the Inducible Nitric Oxide Synthase Gene
Li et al. 2000 Mol. Cell. Biol. 20: 4699
PPARγ Modulates Long Chain Fatty Acid Processing in the Intestinal Epithelium
Duszka et al. 2017 Int. J. Mol. Sci. 18: 2559
PPARγ-induced stimulation of amiloride-sensitive sodium current in renal collecting duct principal cells is serum and insulin dependent
Chraïbi & Renauld 2014 Cell Physiol Biochem 33: 581-593
Role of anaerobic bacteria in the metabolic welfare of the colonic mucosa in man
Roediger 1980 Gut 21: 793-798
The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon
Donohoe et al. 2011 Cell Metab 13(5): 517-526

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Peroxisome proliferator-activated receptor gamma - Wikipedia