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Peroxisome proliferator-activated receptor gamma (PPAR-gamma)

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Peroxisome proliferator-activated receptor gamma (PPAR-gamma) activates mitochondrial beta-oxidation of long-chain and short-chain fatty acids (SCFAs), resulting in oxygen consumption through oxidative phosphorylation
Roediger 1980 Gut 21: 793-798
Donohoe et al. 2011 Cell Metab 13(5): 517-526
Duszka et al. 2017 Int. J. Mol. Sci. 18: 2559

Peroxisome proliferator-activated receptor gamma (PPAR-gamma) can inhibit the transcription of proinflammatory genes, including the iNOS gene (Nos2)
Li et al. 2000 Mo…