meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Asthma & Childhood / Child
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Contents
Childhood asthma is a significant public health challenge. It affects more than 12% of children worldwide. The highest rates are seen in high-income countries.
The maturation of the gut microbiome during the first year of life plays a crucial role in safeguarding against childhood asthma.
Genetic predisposition is crucial, but it's clear that environmental factors, particularly early-life microbial exposures, significantly influence asthma development.
Childhood asthma, if not effectively managed, can result in reduced lung function and serious respiratory issues a…
References (Sources)
- Immunostimulatory CpG Oligonucleotides Abrogate Allergic Susceptibility in a Murine Model of Maternal Asthma Transmission
- Imprinting of the Immune System by the Microbiota Early in Life
- Infant airway microbiota and topical immune perturbations in the origins of childhood asthma
- Risk for Asthma in Offspring of Asthmatic Mothers versus Fathers: A Meta-Analysis.Meta-Analysis
- Sex-specific impact of asthma during pregnancy on infant gut microbiota
- The infant gut bacterial microbiota and risk of pediatric asthma and allergic diseases
- The maternal diet, gut bacteria, and bacterial metabolites during pregnancy influence offspring asthma