meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Tryptophan Metabolism & Pathways
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Contents
The Tryptophan availability is mainly regulated by three pathways: (i) the Kynurenine pathway; (ii) the Serotonin pathway; and (iii) the indole pathway; the latter includes the exogenous production of Indole / Indoles via the microbiome.
Tryptophan-metabolizing pathways also exist in some members of the human gut microbiota, such as Clostridium sporogenes, which can decarboxylate [Trp](brain://Vz--URFdDUqexFe…