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The main building block of intestinal mucus and bacterial source of O-glycans, the MUC2 mucin
The major building block of colonic mucus is the MUC2 mucin, a glycoprotein with about 5,200 amino acids and around 80% glycans, mostly O-glycans
A MUC2 mucin monomer will contain up to 1,600 O-glycans and 30 N-glycans giving more than 3,300 terminal sugar residues, a massive glycan array …