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Shigellosis is a clinical syndrome caused by the invasion of the epithelium lining the terminal ileum, colon, and rectum by Shigella species. This infection occurs globally and affects people of all ages. However, the majority of the disease burden is seen in children aged 1–4 years living in low-income and middle-income settings.
Shigellosis is highly contagious and presents with a range of symptoms:
In addition to these common symptoms, a broad array of uncommon but often severe intestinal and extraintestinal complications can occur.
Despite significant reductions in mortality ove…