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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Acute gastroenteritis / Acute infectious diarrhea

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Contents

Diarrhea may serve as an active host defense mechanism to eliminate pathogens from the gastrointestinal tract, reframing it from being solely a pathological symptom to a beneficial immune response
Hou et al. 2025 Cell Host & Microbe 33: 408-419

Both infectious and UV-inactivated rotavirus and reovirus were found to cause diarrhea in neonatal mice, suggesting that viral replication is not necessary for diarrhea induction. Diarrhea was triggered by the host [immune response](brain://5QFzqPH_7kiBWucrMxK3ow/ImmuneResp…

References (Sources)

Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the Global Burden of Disease Study 2016
GBD 2016 Diarrhoeal Disease Collaborators 2018 Lancet Infect Dis 18: 1211-1228
Global, regional, and national causes of under-5 mortality in 2000-15: an updated systematic analysis with implications for the Sustainable Development Goals
Liu et al. 2016a Lancet 388: 3027-3035
Lactobacillus rhamnosus GG versus Placebo for Acute Gastroenteritis in Children
Schnadower et al. 2018 N Engl J Med 379: 2002-2014
Nonantibiotic prevention and management of recurrent urinary tract infection
Sihra et al. 2018 Nat Rev Urol 15: 750-776
Review
Salmonella epidemiology: A whirlwind of change
Besser 2018 Food Microbiol 71: 55-59
Review
The Role of the Intestinal Epithelium in the "Weep and Sweep" Response during Gastro-Intestinal Helminth Infections
Baska & Norbury 2022 Animals (Basel) 12: 175
Review
Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study
Liu et al. 2016 Lancet 388: 1291-1301

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