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Amyloid precursor protein (APP)
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Contents
The pathogenesis of AD is mainly correlated with the amyloid precursor protein (APP), an integral transmembrane in the protein processing pathway.
Naomi et al. 2022 Nutrients 14: 20
Mutations in APP, Presenilin 1(PSEN1), and Presenilin 2 (PSEN 2) are the primary causes of the early onset of AD.
Naomi et al. 2022 Nutrients 14: 20
APP is transported from trans-Golgi networks through clathrin-mediated endocytosis into the endosomal compartment.
Naomi et al. 2022 Nutrients 14: 20
During this, a fraction of APP is recycled back to the cell surface …