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Enterococcus faecalis
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Contents
Enterococcus faecalis belongs to pathogenic bacteria. Patients with alcoholic hepatitis have increased fecal numbers of E. faecalis. E. faecalis cytolysin, a two-subunit exotoxin, is associated with the severity of liver disease and with mortality in those patients.
It causes direct lysis of hepatocytes and liver damage, likely through its ability to form pores.
Lang & Schnabl 2020 Cell Host & Microbe 28…
References (Sources)
- A product of heme catabolism modulates bacterial function and survival
- Bacteriophage targeting of gut bacterium attenuates alcoholic liver disease
- Co-transfer of vancomycin and other resistance genes from Enterococcus faecalis NCTC12201 to Staphylococcus aureus
- Enterococcus faecalis metalloprotease compromises epithelial barrier and contributes to intestinal inflammation
- Microbiota and Fatty Liver Disease—the Known, the Unknown, and the Future
- Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels