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Acetyl-CoA
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Contents
Acetyl-CoA, the starting material for acetate, butyrate, and propionate, is reached from pyruvate.
Deleu et al. 2021 EBioMedicine 66:103293
Pyruvate can be subsequently converted into acetyl-CoA in the mitochondria to fuel the tricarboxylic acid cycle (TCA) cycle
Gradual consumption of Fructose promotes hepatic [lipogenesis](brain://dzUKKHaiN0ObgGu…
References (Sources)
- Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate
- GS-0976 (Firsocostat): an investigational liverdirected acetyl-CoA carboxylase (ACC) inhibitor for the treatment of non-alcoholic steatohepatitis (NASH)
- How Changes in the Nutritional Landscape Shape Gut ImmunometabolismReview
- Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?