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Glycans / Polysaccharides
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Contents
Glycans are present
- in the diet,
- expressed and secreted by host cells, and
- produced by microbes.
These processes make glycans available to the gut microbiome, positioning them at the interface of diet–microbe–host interactions.
The Vast Majority of Available Sugars in the Large Intestine Are Diet and Host-derived Complex Carbohydrates Which Are Indigestible by the Host
Glycans are recognized by specific glycan binding proteins.
Varki et al. 2009 Essentials of Glycobiology
Definition
[Polysaccharides](brain://lv2gH4oXPEm5p5…
References (Sources)
- Big-Data Glycomics: Tools to Connect Glycan Biosynthesis to Extracellular CommunicationReview
- Glycan Utilisation and Function in the Microbiome of Weaning InfantsReview
- Human Influenza Virus Hemagglutinins Contain Conserved Oligomannose N-Linked Glycans Allowing Potent Neutralization by Lectins
- Plant products as antimicrobial agents
- Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite
- Synthetic glycans control gut microbiome structure and mitigate colitis in mice
- Targeting Gut Microbiota With Natural Polysaccharides: Effective Interventions Against High-Fat Diet-Induced Metabolic Diseases