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Carcinogenesis / Oncogenesis / Tumorigenesis

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Contents

Tumor cells during oncogenesis display unique carbohydrate chains, presenting new targets for cancer immunotherapy.
Mantuano et al. 2020

Although carcinogenesis is defined by de novo genetic alterations, its sustained progression is dependent upon its ability to evade the host’s immunity

Zitvogel et al. 2006 Nat Rev Immunol. 6: 715-27
Yamamoto et al. 2008 Blood 111(6): 3220-4
Schreiber et al. 2011 Science 331:1565-70
Chen & Mellman 2013 Immunity 39: 1–10
Montanari et al. 2015 Clin Adv Hematol Oncol. 13(8): 518-24
Upadhyay et al. 2015 Cancers 7: 736-62
Chen & Mellman 2017 Nature 541(7637): 321-330

Carcinogenesis refers to the complex, multi-step process by which normal cells transform into canc…