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According to the data, different cytokines, including Interleukin-1 (IL-1) beta (IL-1F2), Interleukin-6 (IL-6), and Tumor Necrosis Factor alfa (TNF-alfa), are involved in both term and preterm parturition.
These cytokines could trigger the expression of different substances such as prostaglandins (PGs), their receptors, and PGs synthesizing molecules with already proven roles in parturition.
Hantoushzadeh et al. 2020a Journal of …