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Medical Research Finder

Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

Tumor Necrosis Factor alfa (TNF-alfa)

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Tumor Necrosis Factor alfa (TNF-alfa) acts via Tumor necrosis factor receptor 1 (TNFR1)

The pro-inﬂammatory cytokine Tumor Necrosis Factor alfa (TNF-alfa) plays a crucial role in orchestrating the inﬂammatory response by promoting further production of cytokines and chemokines via TNFR1-induced NFKB activation.
Priem et al. 2020 Trends …

A20 and Cell Death-driven Inflammation
Priem et al. 2020 Trends in Immunology 41: 421
Review
Antagonists of TNF action: clinical experience and new developments
Kontermann et al., 2009
Review
Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: receptors, functions, and roles in diseases
Akdis et al. 2016 J Allergy Clin Immunol 138: 984-1010
Review
Production of complement components by cells of the immune system
Lubbers et al. 2017 Clin Exp Immunol 188: 183-194
Review

12/16/2025