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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Activation / Activators & Dendritic Cells (DCs)

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is associated with upregulation of costimulatory molecules
Wada et al., 2014

Dendritic Cells (DCs) can be activated by CD40L
Gilliet & Liu 2002

The interaction with microorganisms or bacterial products triggers the maturation of DCs from an immature stage to a mature stage, characterized by increased expression of key molecules necessary for T cell activation
Granucci et al. 1999 Microbes and Infection 1(13): 1079-1084

References (Sources)

Generation of Human CD8 T Regulatory Cells by CD40 Ligand–activated Plasmacytoid Dendritic Cells
Gilliet & Liu 2002
The FcgammaRIIa–Syk Axis Controls Human Dendritic Cell Activation and T Cell Response Induced by Infliximab Aggregates
Nabhan et al. 2020 J Immunol 205: 2351
Vaccination With NY-ESO-I Overlapping Peptides Mixed With Picibanil OK-432 and Montanide ISA-51 in Patients With Cancers Expressing the NY-ESO-I Antigen
Wada et al., 2014

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5/29/2026

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