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Dying Cells
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Contents
Dead cells are a dominant source of PAMPs (cells were dying on account of cellular infection) or DAMPs
Dying cells have an important role in the initiation of CD8+ T cell-mediated immunity
Dying Cells as a source of both Antigen and Adjuvant
Dying cells actively generate inducible DAMPs (iDAMPs), i.e., endogenous molecules within dyi…
References (Sources)
- Combination Cancer Therapy with Immune Checkpoint Blockade: Mechanisms and Strategies
- Dying cells actively regulate adaptive immune responsesReview
- Immunogenic cell death and DAMPs in cancer therapy
- Innate and adaptive effects of inflammasomes on T cell response
- The danger model: a renewed sense of self
- TLR-dependent T cell activation in autoimmunityReview
- Tolerogenic dendritic cells