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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Butyrate / Butyric acid & Firmicutes / Bacillota

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Firmicutes (Clostridium IV and XIVa, Eubacterium rectale, Faecalibacterium prausnitzii, and Roseburia intestinalis) primarily produce Butyrate / Butyric acid.
Nobili et al. 2019 Adv Exp Med Biol 1125: 85-100

The third major SCFA, butyrate, is mainly generated from Firmicutes / Bacillota via the butyryl-CoA: acetate CoA transferase enzyme
Louis et al. 2004 J. Bacteri…

References (Sources)

Fighting Fatty Liver Diseases with Nutritional Interventions, Probiotics, Symbiotics, and Fecal Microbiota Transplantation (FMT)
Nobili et al. 2019 Adv Exp Med Biol 1125: 85-100
Review
Restricted distribution of the butyrate kinase pathway among butyrate-producing bacteria from the human colon
Louis et al. 2004 J. Bacteriol. 186: 2099-2106

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12/16/2025

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Butyrate / Butyric acid & Firmicutes / Bacillota

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