meRfi®-GM
The Digital Textbook on Gut Microbiota and Beyond
Asthma & Gut microbiota
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Contents
By associating gut microbial composition from 16S rRNA gene amplicon sequencing during the first year of life with subsequent risk of asthma in 690 participants, 1-year-old children with an immature microbial composition have an increased risk of asthma at age 5 years.
However, this association is only apparent among children born to asthmatic mothers, suggesting that lacking microbial stimulation during the first year of life can trigger their inherited [asthma](brain://GQ7GG…
References (Sources)
- Intestinal microbes in inflammatory bowel diseases.
- Live bacteria in gut microbiome dictate asthma onset triggered by environmental particles via modulation of DNA methylation in dendritic cells
- Maturation of the gut microbiome and risk of asthma in childhood.
- Microbiota–immune interactions in asthma pathogenesis and phenotype
- New developments providing mechanistic insight into the impact of the microbiota on allergic disease.
- The Gut Microbiota in Immune-Mediated Inflammatory Diseases
- The immunology of the allergy epidemic and the hygiene hypothesis