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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

AuthorsReferences (Sources)

AuthorsReferences (Sources)

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Enteroendocrine Hormones

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SCFAs also stimulate secretion of gut hormones, such as glucagon-like peptide 1 (GLP-1) and plasma peptide YY (PYY) involved in Appetite regulation and satiety from enteroendocrine cells proposedly through the SCFA receptors G-Protein Coupled Receptor 41 (GPR41) and G-Protein Coupled Receptor 43 (GPR43), thus playing a role in energy regulation in the body.
Samuel et al. 2008 PNAS 105: 16767-16772
Tolhurst et al. 2012 Diabetes 61: 364–371
Chambers et al. 2015 Gut 64: 1744–1754
Miyamoto et al. 2018a PLoS ONE 13: e0196579

see also:
Enterochromaffin Cells (EC)

References (Sources)

Barley β -glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation in high fat diet fed mice
Miyamoto et al. 2018a PLoS ONE 13: e0196579
Costorage of enteroendocrine hormones evaluated at the cell and subcellular levels in male mice
Fothergill et al. 2017 Endocrinology 158: 2113-2123
Eﬀects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults
Chambers et al. 2015 Gut 64: 1744–1754
Effects of the gut microbiota on host adiposity are modulated by the short-chain fatty-acid binding G protein-coupled receptor, Gpr41
Samuel et al. 2008 PNAS 105: 16767-16772
Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2
Tolhurst et al. 2012 Diabetes 61: 364–371

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