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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Antimicrobial Peptides (AMPs) & Interleukin-22 (IL-22)

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A key protective factor is IL-22 which acts selectively on stromal cells , and mucosal epithelial cells, inducing their survival, proliferation and secretion of antimicrobial peptides
Ouyang et al. 2008 Immunity 28(4): 454–67
Zenewicz et al. 2008 Eur J Immunol. 38: 3265-8
Wu & Shen 2020 Front. Immunol. 11: 554880

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References (Sources)

IL-22 and inflammation: leukin’ through a glass onion
Zenewicz et al. 2008 Eur J Immunol. 38: 3265-8
Innate Lymphoid Cells in Crohn's Disease
Wu & Shen 2020 Front. Immunol. 11: 554880
Review
The biological functions of T helper 17 cell effector cytokines in inflammation.
Ouyang et al. 2008 Immunity 28(4): 454–67

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5/29/2026

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Antimicrobial Peptides (AMPs) & Interleukin-22 (IL-22)

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