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G-Protein Coupled Receptor 43 (GPR43) & Short-chain Fatty Acids (SCFAs)
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Short-chain Fatty Acids (SCFAs) stimulate G-Protein Coupled Receptor 43 (GPR43) on enteroendocrine cells to the secretion of anorectic gut hormones, such as glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). These hormones reach the portal vein and are involved in Appetite regulation and…
References (Sources)
- Antidiabetic (Type 2) Effects of Lactobacillus G15 and Q14 in Rats Through Regulation of Intestinal Permeability and Microbiota
- Control of appetite and energy intake by SCFA: what are the potential underlying mechanisms?
- Functional Characterization of Human Receptors for Short Chain Fatty Acids and Their Role in Polymorphonuclear Cell Activation
- G protein-coupled receptor 43 is essential for neutrophil recruitment during intestinal inflammation
- Identification of a GPR41, FFA2R, expressed on leukocytes and activated by short-chain fatty acids
- Microbiota-Derived Short-Chain Fatty Acids Promote LAMTOR2-Mediated Immune Responses in Macrophages
- Targeting Gut Microbiota: Lactobacillus Alleviated Type 2 Diabetes via Inhibiting LPS Secretion and Activating GPR43 Pathway