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Familial adenomatous polyposis (FAP)
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Contents
Patients with APC gene mutation develop hundreds to thousands of colorectal polyps at young age, of which the disease is termed familial adenomatous polyposis (FAP)
In familial adenomatous polyposis (FAP), a condition where benign precursor lesions (polyps) develop early in life, patchy bacterial biofilms predominantly composed of Escherichia coli and Bacteroides fragilis are found
The Familial Adenomatous Polyposis (FAP)…
References (Sources)
- Familial adenomatous polyposis: clinical presentation, detection and surveillance
- Microbiota dysbiosis and barrier dysfunction in inflammatory bowel disease and colorectal cancers: exploring a common ground hypothesisReview
- Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
- Phenotypic variability of familial adenomatous polyposis in 11 unrelated families with identical APC gene mutation