meRfi®-GM
NCT02944617 - Activia yogurt + VEGFR tyrosine kinases inhibitors vs VEGFR tyrosine kinases inhibitors & Diarrhea (VEGFR tyrosine kinase inhibitors-induced)
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Contents
This randomized clinical trial studies how well probiotic yogurt supplement works in reducing diarrhea in patients with kidney cancer that has spread from the primary site to other places in the body (metastatic) and that are being treated with VEGFR tyrosine kinases inhibitors therapy. Studying samples of blood and stool from patients who eat probiotic yogurt and those who avoid probiotic yogurt may help doctors plan better treatment.
Primary outcome measures:
Number of Participants With Overall Response, Number of Participants With Diarrhea
Results
The probiotic-supplemented group showed increased levels of Bifidobacterium animalis. Clinical benefit rate…