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Among the primary brain tumors, astrocytoma originates from glial cells is the most frequent brain tumor. The most malignant form of astrocytoma is glioblastoma, an incidence rate of 3 per 100,000 persons (1). However, it has been suggested that some internal factors (i.e., genetic elements such as POT1) and external factors (i.e., environmental factors such as ionizing irradiation) could increase the risk of brain tumors (2, 3).
Understanding the mechanisms of involvement of the gut microbiota-brain axis in the development or suppression of brain tumors could establish a new insight for…