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Chronic infections are persistent, long-lasting infections that can have significant impacts on human health. These infections are characterized by the ability of pathogens to evade the immune system and establish a prolonged presence in the host.
T reg cells produce Interleukin-10 (IL-10), a vital adaptation for maintaining immune balance during chronic infections. Interleukin-23 is responsible for causing inflammation in the intestines through both innate and T cell-mediated pathways.
Hue et al. 2006 J Exp Med 203:…