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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Bile Acids / Bile Salts & Inflammatory Bowel Disease (IBD)

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The intestinal bile acid profile is significantly linked to the development of Inflammatory Bowel Disease (IBD). Intestinal diseases like IBD can alter the composition and metabolism of bile acids.
Li et al. 2021g Inflamm Bowel Dis. 27: 1525-1540
Zheng et al. 2022b World J Clin Cases 10(9): 2660-2677

Bile acids function as signal transduction molecules, affecting susceptibility to intestinal inflammation.
Duboc et al. 2013
Song et al. 2019b Nature 577(7790): 410-415
Kuipers et al. 2020 Cell Metab. 31: 445–447
Sinha et al. 2020 Cell Host & Microbe 27: 659-670

In Inflam…

References (Sources)

Alterations in Bile Acid Metabolism Associated With Inflammatory Bowel Disease
Li et al. 2021g Inflamm Bowel Dis. 27: 1525-1540
Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases
Duboc et al. 2013
Dysbiosis-Induced Secondary Bile Acid Deﬁciency Promotes Intestinal Inﬂammation
Sinha et al. 2020 Cell Host & Microbe 27: 659-670
Global chemical effects of the microbiome include new bile-acid conjugations
Quinn et al. 2020 Nature 578: 123-129
Gut microbiome structure and metabolic activity in inflammatory bowel disease
Franzosa et al. 2019
Microbial bile acid metabolites modulate gut RORγ+ regulatory T cell homeostasis
Song et al. 2019b Nature 577(7790): 410-415
Microbiome modulation of the host adaptive immunity through bile acid modification
Kuipers et al. 2020 Cell Metab. 31: 445–447

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Bile Acids / Bile Salts & Inflammatory Bowel Disease (IBD)

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