meRfi®-GM
Colitis / Intestinal inflammation
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Contents
The microbiota present in the mesenteric adipose tissue of individuals with Crohn's disease can induce colitis in mice. The key pathogens Achromobacter pulmonis and Klebsiella variicola are responsible for the exacerbation of colitis. The mesenteric adipose tissue-derived bacterium, Klebsiella variicola, disrupts the intestinal barrier and promotes colitis through the [Type VI secretion system](brain://G3mjfRHmS0WM5kGP6HnP6A/TypeViSe…
References (Sources)
- Fucose Ameliorate Intestinal Inflammation Through Modulating the Crosstalk Between Bile Acids and Gut Microbiota in a Chronic Colitis Murine Model
- Host-microbiota interactions shape local and systemic inflammatory diseasesReview
- Interactions between the microbiota and the immune system
- Mesenteric Adipose Tissue-Derived Klebsiella variicola Disrupts Intestinal Barrier and Promotes Colitis by Type VI Secretion System
- Microbiota in mesenteric adipose tissue from Crohn’s disease promote colitis in mice
- Microcins mediate competition among Enterobacteriaceae in the inflamed gut
- Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels