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Integrin alfa-4-beta-7 is an Integrins that is essential for gut-specific immune responses. It has been targeted for the treatment of inflammatory bowel diseases (IBD). This integrin is found on specific T lymphocytes and is crucial for their movement to the intestinal mucosa.
Integrin alfa-4 beta-7 is a cell adhesion molecule involved in the binding of cells to other cells or to the extracellular matrix (ECM).
It consists of the alfa-4 subunit paired with the beta-7 subunit.
The Integrin alfa-4-beta-7 complex is often…