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In ulcerative colitis, pouchitis is the most common long-term adverse effect following proctocolectomy and ileal pouch-anal anastomosis. Around 5% of patients experience chronic antibiotic-dependent or antibiotic-refractory pouchitis, for which there is no effective treatment (1)
A single-center, double-blinded treatment trial (Parallel Assignment) comparing donor fecal microbiota transplantation with placebo (autologous transplant) in 26 recruited patients with chronic pouchitis
Clinical remission
During the 52-week follow-up period, nine patients in the intervention group…