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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Lewy bodies

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The development of Lewy bodies arises from an initial template formed from pathological Alfa-Synuclein (SNCA), which instigates the seeding of nearby Alfa-Synuclein (SNCA) proteins
Yemula et al. 2021 Journal of Parkinson’s Disease 11: 1491-1505

One of the leading causes of Lewy bodies generation is oxidative stress
Campos-Acuña et al. 2019 Front. Immunol. 10: 239

The Lewy bodies are found in olfactory bulb, [dorsal motor vagal nerve](brain://LsUL5OgeWES…

References (Sources)

Altered Gut Microbiota and Intestinal Permeability in Parkinson’s disease: Pathological highlight to Management
Sharma et al. 2019c
Review
Diﬀuse intracytoplasmic ganglionic inclusions (Lewy type) associated with progressive dementia and quadriparesis in ﬂexion
Okazaki et al. 1961 J Neuropathol Exp Neurol. 20: 237-44
Mutation in the α-synuclein gene identiﬁed in families with Parkinson’s disease
Polymeropoulos et al. 1997 Science 276: 2045-7
Paralysis agitans pathologische anatomie
Lewy 2012 In: Lewandowski M, editor. Handbuch der Neurologie. Berlin: Springer 920–33
Parkinson’s Disease and the Gut: Future Perspectives for Early Diagnosis
Harsanyiova et al. 2020
Review
T-Cell-Driven Inflammation as a Mediator of the Gut-Brain Axis Involved in Parkinson’s Disease
Campos-Acuña et al. 2019 Front. Immunol. 10: 239
Review
The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease
Gibb & Lees 1988 J Neurol Neurosurg Psychiatry 51: 745–52 doi: 10.1136/jnnp.51.6.745

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Lewy bodies

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