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Inducible T-cell costimulator (ICOS) = member of the CD28 superfamily expressed primarily on T lymphocytes
ICOS T-cells produce IFN-gamma
Inducible T-cell costimulator (ICOS) necessary for Interferon Type II (IFN Type II) / Interferon Gamma (IFN-g) production
ICOS T cells are necessary for response to ipilimumab
Dean & Lorigan, 2012
CD4+ cells express Inducible T-cell costimulator (ICOS) on [cell surface](brain://NkBemCu0HFWarB7WVcBVCw/CellSurfac…