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Oral supplementation with gut microbiota-derived short-chain fatty acids (SCFAs), subsequently activating G protein-coupled receptor 43 (GPCR43), enhances a macrophage’s capacity to phagocytose invading K. pneumoniae
Although Gpr109a and Gpr43 are expressed by macrophages, we found that these receptors do not mediate the [anti-inflammatory effects](brain://Yy7Mk78C0k-…