Loading…
Please register to continue your trial period!
meRfi-GM provides you with up-to-date, evidence-based insights on the gut microbiota and related health topics.
Access our ever-expanding digital library and get personalized answers through our interactive AI chat platform.
Start your free trial and transform your understanding of the gut microbiota today!
Lithocholic acid (LCA) is able to directly induce activation and translocation of PKC isoforms, subsequently activating p38 mitogen-activated protein kinase (MAPK) and NF-kB, thereby inhibiting apoptosis.
Fuchs & Trauner 2022 Nat Rev Gastroenterol Hepatol doi: 10.1038/s41575-021-00566-7
The tyrosine kinase receptor, EGFR, activated by LCA, induces phosphorylation of the small [GTPase Ras](brain://1YDGd…