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Angiogenesis is the formation of new blood vessels from pre-existing vasculature in response to external chemical stimuli. This process occurs throughout life
Noradrenaline released by sympathetic adrenergic nerves in prostate cancer can stimulate beta-adrenoceptors in endothelial cells. This leads to the alteration of endothelial cell metabolism toward the inhibition of oxidative phosphorylation and the induction of an angiogenic switch that …