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Uric Acid / Urate (UA) - the end product of the metabolic breakdown of purines in humans - when its concentration reaches saturation levels, forms pro-inflammatory crystals that are deposited in joints (e.g. gout)
A significant portion of Uric Acid / Urate is excreted in the gut
Uric Acid / Urate exacerbates inflammation and endothelial dysfunction, increases activity of the renin-angiotensin-aldosterone system, and is increased in patients wi…