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Interleukin-18 Receptor 1 (IL-18R1)

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Interleukin-18 Receptor 1 (IL-18R1) is structurally very similar to IL-1R / Interleukin-1 Receptor
Dostert et al. 2013

Interleukin-18 Receptor 1 (IL-18R1) forms a complex with the Interleukin 18 Receptor Accessory Protein (IL18RAP) to create a functional receptor for Interleukin-18 (IL-18). This complex is responsible for high-affinity IL-18 binding and signal transduction.
Ma et al. 2021 Cells 10(5): 964

Interleukin-18 Receptor 1 (IL-18R1) plays a critical role in mediating inflammatory responses and has emerged as a potential therapeutic target for a range …