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Gut microbiota / Evidence-based microbiome knowledge (incl. AI chat)
Prebiotics, Probiotics, FMT / Manipulators of the Intestinal Microbiota

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Pancreatic Ductal Adenocarcinoma (PDAC) (Mismatch Repair Deﬁciency (MMR-d) / DNA Mismatch Repair / Microsatellite Instability (MSI))

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MMR deficiency and potential MSI-H status have been recognized as important prognostic biomarkers for patients with pancreatic cancer. Patients with MSI-H status tend to be younger and exhibit unique tumor characteristics.
Bodea et al. 2026 J Clin Med 15(4): 1411

DNA mismatch repair proteins (MMR with MSI-H) have showed excellent responses in PDAC, which is about 3% of PDAC
Chandana et al. 2019

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References (Sources)

Mismatch Repair Protein and Microsatellite Instability Analysis in Pancreatic Ductal Adenocarcinoma
Bodea et al. 2026 J Clin Med 15(4): 1411
Therapeutic trends in pancreatic ductal adenocarcinoma (PDAC)
Chandana et al. 2019

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5/30/2026

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Pancreatic Ductal Adenocarcinoma (PDAC) (Mismatch Repair Deﬁciency (MMR-d) / DNA Mismatch Repair / Microsatellite Instability (MSI))

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