meRfi®-GM
Naive T cells / Th0 cells
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Contents
Naive T cells / Th0 cells (Tn) are activated and expanded upon stimulation by antigen, giving rise to effector and memory T cells that can mediate immediate and long-term protection
The mesenteric lymph nodes (MLN) and gut-associated lymphoid tissue (GALT) are the main location for priming naïve T-cell responses
Activation through Signal 2 (co-stimulation); Signal 2 Is Produced by Signal 0
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References (Sources)
- CD4(+) T-cell subsets in intestinal inflammation
- Immunometabolism: A target for the comprehension of immune response toward transplantation
- Molecular regulation of effector and memory T cell differentiation
- Naive CD4+ T Cells Carrying a TLR2 Agonist Overcome TGF-b–Mediated Tumor Immune Evasion
- The ABC of clinical and experimental adjuvants—A brief overview