meRfi®-GM
Gut-Associated Lymphoid Tissues (GALTs)
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Contents
Naive and memory B cells encounter antigens that are transported into the structure by M cells. When an antigen-specific naive or memory B-cell encounters an antigen via its BCR, it is activated. After activation, antigen-specific B cells proliferate within the subepithelial dome.
Bemark et al. 2024 J Immunol 45(3): 211
The GI mucosa is considered the biggest human lymphoid organ.
Gut-associated, lymphoi…
References (Sources)
- Blood vessels of the Peyer's patch in the mouse: I. Topographic studies
- Expression of the IRTA1 receptor identifies intraepithelial and subepithelial marginal zone B cells of the mucosa-associated lymphoid tissue (MALT)
- Gut microbiome and neurosurgery: Implications for treatment
- Inulin, oligofructose and immunomodulation
- Man the barrier! Strategic defences in the intestinal mucosaReview
- Role of the gut microbiota in immunity and inflammatory disease.
- The role of the immune system in governing host-microbe interactions in the intestine