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Individuals experiencing depression frequently exhibit changes in their gut microbiome. This alteration is characterized by an increase in pro-inflammatory bacteria and a decrease in anti-inflammatory bacteria (1, 2, 3, 4). These findings suggest the involvement of the Brain-Gut-Microbiome Axis (MGBA) in Major depressive disorder / Major Depression / Depressive episode (MDD) (5).
It is largely unknown whether dysbiosis activates [T cell differentiation](brain…