Epigallocatechin gallate (EGCG)

Epigallocatechin gallate (EGCG) is the main flavanol (or Flavan-3-ol or catechin) present in green tea extracts.

Epigallocatechin3-gallate (EGCG) possesses anti-inflammatory and anti-oxidative properties
Gan et al. 2018a Crit Rev Food Sci Nutr. 58(6): 924-41
Chikara et al. 2018 Cancer Lett. 413: 122-34

Epigallocatechin-3-gallate (EGCG), a major bioactive constituent of green tea, is known to be beneficial in IBD alleviation
Wu et al. 2021f Microbiome 9: 184

For example, the concentration of Epigallocatechin gallate (EGCG)/Epigallocatechin-3-gallate (EGCG)) from green tea in the organs and blood is only 0.0003–0.4500% of the administered dose
Nakagawa & Miyazawa 1997 J Nutr Sci Vitaminol (Tokyo) 43: 679-684

EGCG & Experimental Colitis

We observed a distinct Epigallocatechin gallate (EGCG)-mediated alteration in the gut microbiome by increasing Akkermansia abundance and butyrate production after oral application
Wu et al. 2021f Microbiome 9: 184

Also, Prophylactic EGCG attenuated colitis and significantly enriched short-chain fatty acids (SCFAs)-producing bacteria such as Akkermansia and SCFAs production in DSS-induced mice
Wu et al. 2021f Microbiome 9: 184

see also:
Gut microbiota & Tea
Green Tea Polyphenols & Gut microbiota